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NDUFS8 Antikörper (Internal Region)

NDUFS8 Reaktivität: Human, Maus, Ratte, Hund WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN499135
  • Target Alle NDUFS8 Antikörper anzeigen
    NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))
    Bindungsspezifität
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 39
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 35
    • 3
    • 2
    Ziege
    Klonalität
    • 40
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NDUFS8 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 16
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    C-EAEIAANIQA D
    Spezifität
    Recognizes NDUFS8.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Canine.
    Species reactivity (tested):Human, Rat.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_002487.1. Genename: NDUFS8
    Top Product
    Discover our top product NDUFS8 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Limit Dilution: 1/4000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 25 kDa in Mouse and RatHeart lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))
    Andere Bezeichnung
    NDUFS8 (NDUFS8 Produkte)
    Synonyme
    CI-23k antikoerper, CI23KD antikoerper, TYKY antikoerper, BC021616 antikoerper, CI-23kD antikoerper, ndufs8 antikoerper, wu:fb30b07 antikoerper, zgc:65835 antikoerper, zgc:77840 antikoerper, MGC85457 antikoerper, ND23 antikoerper, GB17476 antikoerper, DDBDRAFT_0169117 antikoerper, DDBDRAFT_0233205 antikoerper, DDB_0169117 antikoerper, DDB_0233205 antikoerper, zgc:109991 antikoerper, NADH:ubiquinone oxidoreductase core subunit S8 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 8 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 8a antikoerper, NADH:ubiquinone oxidoreductase core subunit S8 L homeolog antikoerper, NADH-quinone oxidoreductase subunit I antikoerper, NADH dehydrogenase Fe-S protein 8 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 8b antikoerper, NDUFS8 antikoerper, Ndufs8 antikoerper, ndufs8a antikoerper, ndufs8.L antikoerper, ndufs8 antikoerper, LOC551078 antikoerper, ndufs8b antikoerper
    Hintergrund
    NDUFS8 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (may donate electrons to ubiquinone). Defects in NDUFS8 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.Synonyms: CI-23kD, Complex I-23kD, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit, mitochondrial
    Molekulargewicht
    24.0kDa (Mouse NP_659119.2 and Rat NP_001099792.1).
    Gen-ID
    4728
    NCBI Accession
    NP_002487
    UniProt
    O00217
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