HCST Antikörper (Hematopoietic Cell Signal Transducer) (C-Term)

Details for Product anti-HCST Antibody No. ABIN5553692, Anbieter: Anmelden zum Anzeigen
Antigen
  • HCST
  • DAP10
  • KAP10
  • PIK3AP
  • Dap10
  • hematopoietic cell signal transducer
  • HCST
  • hcst
  • Hcst
Epitop
C-Term
12
2
1
1
1
Reaktivität
Human
30
1
1
1
Wirt
Ziege
15
15
Klonalität
Polyklonal
Konjugat
Dieser HCST Antikörper ist unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
15
13
13
3
Optionen
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Immunogen Peptide with sequence C-RSPAQEDGKVYIN, from the C Terminus of the protein sequence
Spezifität This antibody is expected to recognize isoform 1 (NP_055081.1) but it may recognize isoform 2 lacking residue E81 (NP_001007470.1).
Kreuzreaktivität (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Reinigung Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography
Andere Bezeichnung DAP10 / HCST (HCST Antibody Abstract)
Hintergrund HCST is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. It may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D and may activate phosphatidylinositol 3-kinase dependent signaling pathways. The receptor complex containing HCST may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.Synonyms: DNAX-activation protein 10, Hematopoietic cell signal transducer, KAP10, Membrane protein DAP10, PIK3AP, Transmembrane adapter protein KAP10
Gen-ID 10870
NCBI Accession NP_001007470
UniProt Q9UBK5
Applikationshinweise Peptide ELISA: 1/128000. Western Blot: 0.2-0.6 μg/mL. Approx 40 kDa band observed in Human spleen lysates (calculated MW of 9.0 kDaaccording to NP_055081.1). An additional band of unknown identity was also consistentlyobserved at 100 kDa. This band was successfully blocked by incubation with theimmunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.