KCNJ1 Antikörper (Internal Region)

Produktnummer ABIN375086

Produktdetails anti-KCNJ1 Antikörper

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KCNJ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-DQININFVVD AGNEN

Spezifität: This antibody is expected to recognize reported isoforms (NP_722449.2 and NP_000211) of KCNJ1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_000211.1, NP_722448.1. Genename: KCNJ1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Andere Bezeichnung: KCNJ1 (KCNJ1 Produkte)

Synonyme: KIR1.1 antikoerper, ROMK antikoerper, ROMK1 antikoerper, kir1.1 antikoerper, romk1 antikoerper, Kcnj antikoerper, Kir1.1 antikoerper, Romk2 antikoerper, kcnj1 antikoerper, wu:fl37c05 antikoerper, zgc:63534 antikoerper, potassium voltage-gated channel subfamily J member 1 antikoerper, potassium voltage-gated channel subfamily J member 1 L homeolog antikoerper, potassium inwardly-rectifying channel, subfamily J, member 1 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antikoerper, KCNJ1 antikoerper, kcnj1.L antikoerper, kcnj1 antikoerper, Kcnj1 antikoerper, kcnj1a.1 antikoerper

Hintergrund: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ1 is an integral membrane protein and inward rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The KCNJ1 channel is blocked by external barium. WNK1 has been shown to inhibit KCNJ1 by enhancing its endocytosis. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure.Synonyms: ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectifier potassium channel 1, KCNJ1, Kir1.1, Potassium channel, ROMK1, inwardly rectifying subfamily J member 1

Gen-ID: 3758

NCBI Accession: NP_000211

UniProt: P48048