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ABCC11 Antikörper (Internal Region)

ABCC11 Reaktivität: Human, Hund, Rind (Kuh) WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN375006
  • Target Alle ABCC11 Antikörper anzeigen
    ABCC11 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 35
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Hund, Rind (Kuh)
    Wirt
    • 30
    • 5
    • 1
    • 1
    Ziege
    Klonalität
    • 33
    • 4
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABCC11 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 20
    • 18
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to MRP8 / ABCC11.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine, Bovine.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence C-KVVEFDRPEVLRK, from the internal region (near C Terminus) of the protein sequence
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  • Applikationshinweise
    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ABCC11 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))
    Andere Bezeichnung
    ABCC11 / MRP8 (ABCC11 Produkte)
    Synonyme
    EWWD antikoerper, MRP8 antikoerper, WW antikoerper, ATP binding cassette subfamily C member 11 antikoerper, ABCC11 antikoerper
    Hintergrund
    ABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.Synonyms: ATP-binding cassette transporter sub-family C member 11
    Gen-ID
    85320, 9606
    UniProt
    Q96J66
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