PTP4A1 Antikörper (C-Term)

Produktnummer ABIN374988

Produktdetails anti-PTP4A1 Antikörper

Target: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PTP4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: KDSNGHRNNC CIQ

Spezifität: This antibody reacts to PTP4A1 / PRL-1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence (NP_003454.1). Genename: PTP4A1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTP4A1

Target: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Andere Bezeichnung: PTP4A1 / PRL1 (PTP4A1 Produkte)

Synonyme: ptp4a1 antikoerper, MGC83351 antikoerper, hh72 antikoerper, prl1 antikoerper, prl-1 antikoerper, MGC79517 antikoerper, ptpcaax1 antikoerper, ptp(caax1) antikoerper, fb54d08 antikoerper, fc01c04 antikoerper, wu:fb54d08 antikoerper, wu:fc01c04 antikoerper, zgc:101726 antikoerper, Ptp4a1 antikoerper, PRL-1 antikoerper, PTP4A1 antikoerper, PRL1 antikoerper, DKFZp459E022 antikoerper, AA415290 antikoerper, AU019864 antikoerper, C130021B01 antikoerper, Prl-1 antikoerper, HH72 antikoerper, PTP(CAAX1) antikoerper, PTPCAAX1 antikoerper, protein tyrosine phosphatase type IVA, member 1 antikoerper, protein tyrosine phosphatase type IVA, member 1 L homeolog antikoerper, protein tyrosine phosphatase 4a1 antikoerper, PTP4A1 antikoerper, ptp4a1.L antikoerper, ptp4a1 antikoerper, Ptp4a1 antikoerper

Hintergrund: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.Synonyms: PRL-1, PTP(CAAXI), PTPCAAX1, Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1

Gen-ID: 7803

NCBI Accession: NP_003454

UniProt: Q93096