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APPL1 Antikörper (Internal Region)

APPL1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374837
  • Target Alle APPL1 Antikörper anzeigen
    APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
    Bindungsspezifität
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 38
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund
    Wirt
    • 34
    • 2
    • 2
    Ziege
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APPL1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 14
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    C-NRYSRLSKKR ENDK
    Spezifität
    This antibody recognizes APPL1.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_036228.1.
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    Discover our top product APPL1 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 80 kDa band observed in Rat Aortic Smooth SkeletalMuscle Cells (lane 1), intensity increased after infection with Human APPL1 adenovirus for48h (lane 2). Calculated MW of 79.0 kDa according to NP_036228.1. The blot wasco-labeled with Tubulin-specific antibodies as a loading control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
    Andere Bezeichnung
    APPL1 / DIP13A (APPL1 Produkte)
    Synonyme
    APPL antikoerper, DIP13alpha antikoerper, 2900057D21Rik antikoerper, 7330406P05Rik antikoerper, AI585782 antikoerper, AW209077 antikoerper, BB022931 antikoerper, C88264 antikoerper, DIP13 antikoerper, RGD1309388 antikoerper, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 antikoerper, adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 antikoerper, APPL1 antikoerper, Appl1 antikoerper
    Hintergrund
    APPL is involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The APPL binds to RAB5A/Rab5 through N-terminal domain. This interaction is essential for its recruitment to endosomal membranes as well as its role in cell proliferation.Synonyms: Adapter protein containing PH domain, DCC-interacting protein 13-alpha, Dip13-alpha, KIAA1428, PTB domain and leucine zipper motif 1
    Gen-ID
    26060, 9606
    UniProt
    Q9UKG1
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