SECISBP2 Antikörper (Internal Region)

Produktnummer ABIN374739

Produktdetails anti-SECISBP2 Antikörper

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SECISBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-KERQERKQRL QEN

Spezifität: This antibody recognizes SBP2.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Pig, Cow.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatpography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_076982.3.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Andere Bezeichnung: SECISBP2 (SECISBP2 Produkte)

Hintergrund: SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.Synonyms: SBP2, SECIS-binding protein 2, Selenocysteine insertion sequence-binding protein 2

Gen-ID: 79048

NCBI Accession: NP_076982

UniProt: Q96T21