LIM Domain Binding 3 Protein Antikörper (Internal Region)

Produktnummer ABIN374603

Produktdetails anti-LIM Domain Binding 3 Protein Antikörper

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser LIM Domain Binding 3 Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to LDB3.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Porcine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-KSQNKPEDEADE, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/2000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LIM Domain Binding 3 Protein

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Andere Bezeichnung: LDB3 (LDB3 Produkte)

Synonyme: CMD1C antikoerper, CYPHER antikoerper, LDB3Z1 antikoerper, LDB3Z4 antikoerper, LVNC3 antikoerper, MFM4 antikoerper, ORACLE antikoerper, PDLIM6 antikoerper, ZASP antikoerper, AW742271 antikoerper, ldb3l antikoerper, zgc:55814 antikoerper, wu:fi31d08 antikoerper, ldb3 antikoerper, MGC52706 antikoerper, MGC75668 antikoerper, RGD1564875 antikoerper, LDB3 antikoerper, cypher antikoerper, hm:zehn1639 antikoerper, zehn1639 antikoerper, LIM domain binding 3 antikoerper, LIM domain binding 3b antikoerper, LIM domain binding 3 S homeolog antikoerper, LIM domain binding 3a antikoerper, LDB3 antikoerper, Ldb3 antikoerper, ldb3b antikoerper, ldb3.S antikoerper, ldb3 antikoerper, ldb3a antikoerper

Hintergrund: LDB3 (LIM domain-binding protein 3) may function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. It interactes with various PKC isoforms and with the C-terminal region of ACTN2 via its LIM and PDZ domains respectively. It also interacts with MYOZ1, MYOZ2 and MYOZ3. 6 isoforms are produced by alternative splicing. Defects in LDB3 are a cause of dilated cardiomyopathy 1A, a disorder characterized by cardiac dilation and reduced systolic function, as well as ZASP-related myofibrillar myopathy, an autosomal dominant myopathy that is characterized by distal muscle weakness with signs of cardiomyopathy and neuropathy.Synonyms: KIAA0613, LIM domain-binding protein 3, ZASP

Gen-ID: 11155, 9606

UniProt: O75112