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FBXW2 Antikörper (C-Term)

FBXW2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein WB, IHC (p) Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374352
  • Target Alle FBXW2 Antikörper anzeigen
    FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 29
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Schwein
    Wirt
    • 27
    • 1
    • 1
    Ziege
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXW2 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 10
    • 10
    • 5
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Sequenz
    C-KRGSSFLAGE HPG
    Spezifität
    This antibody detects FBXW2 / FBW2 / FWD2 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine (Dog), Pig, Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Synthetic peptide from C-Terminus of the protein sequence according to NP_036296.1 Genename: FBXW2
    Top Product
    Discover our top product FBXW2 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.3-1.5 μg/mL. Approx 48 kDa band observed in Human Kidney lysates(calculated MW of 48.8 kDa according to NP_036296.1). A stronger band of unknownidentity was also consistently observed at appr.38 kDa - both bands were successfullyblocked by incubation with the immunising peptide. Immunohistochemistry: 2-3 μg/mL. In paraffin embedded Human Kidney, showscytoplasmic staining of epithelial cells in some renal tubules.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
    Andere Bezeichnung
    FBXW2 / FBW2 / FWD2 (FBXW2 Produkte)
    Synonyme
    FBXW2 antikoerper, md6 antikoerper, fbw2 antikoerper, fwd2 antikoerper, MGC53244 antikoerper, FBW2 antikoerper, Fwd2 antikoerper, Md6 antikoerper, wu:fc72f10 antikoerper, zgc:110365 antikoerper, 2700071L08Rik antikoerper, MD6 antikoerper, F-box and WD repeat domain containing 2 antikoerper, F-box and WD repeat domain containing 2 L homeolog antikoerper, F-box and WD-40 domain protein 2 antikoerper, FBXW2 antikoerper, fbxw2 antikoerper, Fbxw2 antikoerper, fbxw2.L antikoerper
    Hintergrund
    F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.Synonyms: F-box and WD-40 domain-containing protein 2, F-box/WD repeat-containing protein 2, Protein MD6
    Gen-ID
    26190
    NCBI Accession
    NP_036296
    UniProt
    Q9UKT8
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