PRKD3 Antikörper (Middle Region)

Produktnummer ABIN359071

Produktdetails anti-PRKD3 Antikörper

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts to PKC nu.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PKC nu.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Immunofluorescence: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: 1. Jun Chen, et al. Cancer Res. , May 2008, 68: 3844 - 3853.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Andere Bezeichnung: PRKD3 (PRKD3 Produkte)

Synonyme: EPK2 antikoerper, PKC-NU antikoerper, PKD3 antikoerper, PRKCN antikoerper, nPKC-NU antikoerper, PRKD3 antikoerper, 4930557O20Rik antikoerper, 5730497N19Rik antikoerper, Pkcnu antikoerper, Prkcn antikoerper, protein kinase D3 antikoerper, PRKD3 antikoerper, prkd3 antikoerper, Prkd3 antikoerper

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.Synonyms: EPK2, PKC nu, PKC-nu, PRKCN, Protein kinase C nu type, Serine/threonine-protein kinase D3, nPKC-nu

Gen-ID: 23683, 9606

UniProt: O94806