TNFSF14 Antikörper (Internal Region)

Produktnummer ABIN452686

Produktdetails anti-TNFSF14 Antikörper

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TNFSF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: c-HEVNPAAHLT GANS

Spezifität: This antibody recognizes Human LIGHT. It is expected to recognize both reported isoforms (NP_003798.2, NP_742011.1). Other species not tested.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003798.2, NP_742011.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu TNFSF14

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Andere Bezeichnung: CD258 / LIGHT (TNFSF14 Produkte)

Synonyme: TNFSF14 antikoerper, CD258 antikoerper, HVEML antikoerper, LIGHT antikoerper, LTg antikoerper, TR2 antikoerper, HVEM-L antikoerper, Ly113 antikoerper, TNF superfamily member 14 antikoerper, tumor necrosis factor (ligand) superfamily, member 14 antikoerper, TNFSF14 antikoerper, Tnfsf14 antikoerper

Hintergrund: LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors, the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).Synonyms: HVEM-L, HVEML, Herpesvirus entry mediator-ligand, TNFSF14, Tumor necrosis factor ligand superfamily member 14

Gen-ID: 8740

NCBI Accession: NP_003798

UniProt: O43557

Pathways: Cancer Immune Checkpoints