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ASAP1 Antikörper (pTyr782)

ASAP1 Reaktivität: Maus, Human, Rind (Kuh), Ratte, Hund WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401326
  • Target Alle ASAP1 Antikörper anzeigen
    ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 777-787, pTyr782
    Reaktivität
    • 43
    • 35
    • 10
    • 6
    • 1
    • 1
    • 1
    Maus, Human, Rind (Kuh), Ratte, Hund
    Wirt
    • 52
    • 2
    • 1
    Kaninchen
    Klonalität
    • 53
    • 2
    Polyklonal
    Konjugat
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASAP1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 26
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (expected):Human, Chicken, Bovine, Canine, Rat, Chimpanzee.
    Species reactivity (tested):Mouse.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Synthetic peptide corresponding to amino acids 777-787 of mouse ASAP1 protein
    Isotyp
    IgG
    Top Product
    Discover our top product ASAP1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/4,000 - 1/16,000. Western Blot: 1/500 - 1/2,000. Immunohistochemistry: 20-40 μg/mL. Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.09 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
  • Target
    ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
    Andere Bezeichnung
    ASAP1 / DDEF1 (ASAP1 Produkte)
    Synonyme
    AV239055 antikoerper, DEF-1 antikoerper, Ddef1 antikoerper, PAP antikoerper, mKIAA1249 antikoerper, s19 antikoerper, AMAP1 antikoerper, CENTB4 antikoerper, DDEF1 antikoerper, PAG2 antikoerper, ZG14P antikoerper, ASAP1 antikoerper, ddef1 antikoerper, Asap1 antikoerper, si:ch211-160i2.3 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain1 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 antikoerper, toxic extracellular endopeptidase antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a antikoerper, Asap1 antikoerper, ASAP1 antikoerper, asaP1 antikoerper, asap1 antikoerper, asap1.L antikoerper, asap1a antikoerper
    Hintergrund
    ASAP1 (also known as AMAP1, 130- kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, PIP2-dependent ARF1 GAP,ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, Differentiation-enhancing factor 1, DEF-1) is an Arf-directed GTPase activating protein that is a substrate for the kinases Src and FAK and has been implicated in the regulation of membrane traffic, focal adhesions and invadopodia/podosomes. Phosphorylation of ASAP1 at tyrosine 782 has been found to affect enzymatic and some biological activities, including the function of invadopodia. ASAP1 is expressed in many tissues but is most abundant in the testis, brain, lung and spleen. A heightened expression was seen in the adipose tissue from obese (ob) and diabetic (db) animals. Multiple transcript variants have been reported for this protein.Synonyms: 130 kDa phosphatidylinositol 4, 5-biphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, AMAP1, ANK repeat and PH domain-containing protein 1, Arf-GAP with SH3 domain, CENTB4, Development and differentiation-enhancing factor 1, KIAA1249, PAG2, PIP2-dependent ARF1 GAP, ZG14P
    Gen-ID
    10090
    UniProt
    Q9QWY8
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