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AGAP2 Antikörper (N-Term)

AGAP2 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401036
  • Target Alle AGAP2 Antikörper anzeigen
    AGAP2 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
    Bindungsspezifität
    • 15
    • 15
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-836, N-Term
    Reaktivität
    • 47
    • 17
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 1
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AGAP2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 21
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is directed against AGAP2 protein.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 1-836 of human AGAP2 protein.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA: 1/40000 - 1/200000. Western Blot: 1/5000 - 1/20000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with 50 μL deionized water or equivalent.
    Konzentration
    2.0 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    AGAP2 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
    Andere Bezeichnung
    AGAP2 / CENTG1 (AGAP2 Produkte)
    Synonyme
    zgc:153779 antikoerper, CENTG1 antikoerper, GGAP2 antikoerper, PIKE antikoerper, Centg1 antikoerper, mKIAA0167 antikoerper, Pike antikoerper, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 antikoerper, AGAP2 antikoerper, agap2 antikoerper, Agap2 antikoerper
    Hintergrund
    AGAP2 (also known as centauringamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidylinositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.Synonyms: Arf-GAP GTPase ANK repeat and PH domain-containing protein 2, Centaurin-gamma-1, GGAP2, GTP-binding and GTPase-activating protein 2, KIAA0167, PIKE, Phosphatidylinositol-3-kinase enhancer
    Gen-ID
    116986
    NCBI Accession
    NP_001116244
    UniProt
    Q99490
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