DLG2 Antikörper (N-Term)

Produktnummer ABIN492455

Produktdetails anti-DLG2 Antikörper

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Bindungsspezifität: AA 1-852, N-Term

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DLG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Detects ~110 kDa protein. No cross-reactivity against other MAGUK family members PSD95, SAP97, SAP102 expressed in transfected cells.

Produktmerkmale: Synonyms: Disks large homolog 2, PSD-93, Chapsyn-110, Postsynaptic density protein PSD-93,Channel-associated protein of synapse-110

Aufreinigung: Protein G Chromatography.

Immunogen: Fusion protein amino acids 1-852 of Rat Chapsyn-110 (Accession number Q63622).

Klon: S18-30

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Chapsyn-110 in 10 μg of rat brain lysate bycolorimetric immunoblot analysis using Goat anti-mouse IgG: HRP as the secondaryantibody. Immunoprecipitation.1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Andere Bezeichnung: DLG2 / PSD93 (DLG2 Produkte)

Synonyme: PPP1R58 antikoerper, PSD-93 antikoerper, PSD93 antikoerper, chapsyn-110 antikoerper, A330103J02Rik antikoerper, B230218P12Rik antikoerper, B330007M19Rik antikoerper, Dlgh2 antikoerper, Gm1197 antikoerper, discs, large homolog 2 (Drosophila) antikoerper, discs large MAGUK scaffold protein 2 antikoerper, dlg2 antikoerper, DLG2 antikoerper, Dlg2 antikoerper

Hintergrund: Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80 % identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2).Synonyms: Channel-associated protein of synapse-110, Chapsyn-110, Disks large homolog 2, PSD-93, Postsynaptic density protein PSD-93

Gen-ID: 64053

UniProt: Q63622