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PDGFRA Antikörper (C-Term)

PDGFRA Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5515866
  • Target Alle PDGFRA Antikörper anzeigen
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Bindungsspezifität
    • 23
    • 16
    • 16
    • 15
    • 15
    • 14
    • 11
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 247
    • 130
    • 70
    • 18
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 221
    • 41
    • 9
    • 1
    Kaninchen
    Klonalität
    • 213
    • 59
    Polyklonal
    Konjugat
    • 116
    • 22
    • 19
    • 16
    • 15
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    Dieser PDGFRA Antikörper ist unkonjugiert
    Applikation
    • 180
    • 114
    • 72
    • 54
    • 54
    • 47
    • 38
    • 24
    • 24
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    SGYIIPLPDI DPVPEEEDLG KRNRHSSQTS EESAIETGSS SSTFIKREDE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PGFRA. It was validated on Western Blot.
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen for Anti-PDGFRA antibody is: synthetic peptide directed towards the C-terminal region of Human PGFRA
    Top Product
    Discover our top product PDGFRA Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Andere Bezeichnung
    PDGFRA (PDGFRA Produkte)
    Synonyme
    AI115593 antikoerper, CD140a antikoerper, Pdgfr-2 antikoerper, APDGFR antikoerper, PDGFACE antikoerper, CD140A antikoerper, PDGFR-2 antikoerper, PDGFR2 antikoerper, RHEPDGFRA antikoerper, PDGFR antikoerper, PDGFR-A antikoerper, platelet derived growth factor receptor alpha antikoerper, platelet derived growth factor receptor, alpha polypeptide antikoerper, platelet-derived growth factor receptor, alpha polypeptide L homeolog antikoerper, platelet-derived growth factor receptor, alpha polypeptide antikoerper, PDGFRA antikoerper, Pdgfra antikoerper, pdgfra.L antikoerper
    Hintergrund
    This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

    Alias Symbols: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA

    Protein Interaction Partner: CCDC155, SRPK1, FBXO25, ULBP2, UBC, TGFBR2, PIK3R1, KIT, Nedd4, GRB2, PTEN, SHF, SNX6, PDGFC, SNX4, SNX2, SLC9A3R1, STAT5B, CRKL, GRB14, STAT5A, CAV1, STAT1, SHB, ITGAV, PDGFB, PTPN11, PDGFRA, ITGB3, PDGFA, PDGFRB, PLCG1, CBL, CRK, JAK1, STAT3, CAV3,

    Protein Size: 1089
    Gen-ID
    5156
    UniProt
    P16234
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
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