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B3GAT3 Antikörper (AA 1-335)

B3GAT3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
Produktnummer ABIN525639
  • Target Alle B3GAT3 Antikörper anzeigen
    B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-335
    Reaktivität
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 19
    • 4
    Maus
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser B3GAT3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 15
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Mouse polyclonal antibody raised against a full-length human B3GAT3 protein.
    Sequenz
    MKLKLKNVFL AYFLVSIAGL LYALVQLGQP CDCLPPLRAA AEQLRQKDLR ISQLQAELRR PPPAPAQPPE PEALPTIYVV TPTYARLVQK AELVRLSQTL SLVPRLHWLL VEDAEGPTPL VSGLLAASGL LFTHLVVLTP KAQRLREGEP GWVHPRGVEQ RNKALDWLRG RGGAVGGEKD PPPPGTQGVV YFADDDNTYS RELFEEMRWT RGVSVWPVGL VGGLRFEGPQ VQDGRVVGFH TAWEPSRPFP VDMAGFAVAL PLLLDKPNAQ FDSTAPRGHL ESSLLSHLVD PKDLEPRAAN CTRVLVWHTR TEKPKMKQEE QLQRQGRGSD PAIEV
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    B3GAT3 (NP_036332.2, 1 a.a. ~ 335 a.a) full-length human protein.
    Top Product
    Discover our top product B3GAT3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Job, Mizumoto, Smith, Couser, Brazil, Saal, Patterson, Gibson, Soden, Miller, Thiffault, Saunders, Yamada, Hoffmann, Sugahara, Farrow: "Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype." in: BMC medical genetics, Vol. 17, Issue 1, pp. 86, (2016) (PubMed).

    Budde, Mizumoto, Kogawa, Becker, Altmüller, Thiele, Rüschendorf, Toliat, Kaleschke, Hämmerle, Höhne, Sugahara, Nürnberg, Kennerknecht: "Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3." in: Human genetics, Vol. 134, Issue 7, pp. 691-704, (2015) (PubMed).

    Baasanjav, Al-Gazali, Hashiguchi, Mizumoto, Fischer, Horn, Seelow, Ali, Aziz, Langer, Saleh, Becker, Nürnberg, Cantagrel, Gleeson, Gomez, Michel, Stricker, Lindner, Nürnberg, Sugahara, Mundlos et al.: "Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. ..." in: American journal of human genetics, Vol. 89, Issue 1, pp. 15-27, (2011) (PubMed).

    Hiyama, Gajghate, Sakai, Mochida, Shapiro, Risbud: "Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9824-34, (2009) (PubMed).

  • Target
    B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))
    Andere Bezeichnung
    B3GAT3 (B3GAT3 Produkte)
    Synonyme
    GLCATI antikoerper, 2810405M13Rik antikoerper, GlcUAT-I antikoerper, Glcat-i antikoerper, beta-1,3-glucuronyltransferase 3 antikoerper, beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) antikoerper, B3GAT3 antikoerper, B3gat3 antikoerper
    Hintergrund
    Full Gene Name: beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
    Synonyms: GLCATI,GlcAT-I
    Gen-ID
    26229
    NCBI Accession
    NM_012200
    Pathways
    Glycosaminoglycan Metabolic Process
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