PFKFB3 Antikörper (AA 412-520)

Produktnummer ABIN518808

Produktdetails anti-PFKFB3 Antikörper

Target: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Bindungsspezifität: AA 412-520

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PFKFB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant PFKFB3.

Sequenz: CPLHTVLKLT PVAYGCRVES IYLNVESVCT HRERSEDAKK GPNPLMRRNS VTPLASPEPT KKPRINSFEE HVASTSAALP SCLPPEVPTQ LPGQNMKGSR SSADSSRKH

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: PFKFB3 (NP_004557, 412 a.a. ~ 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3F3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PFKFB3 Antikörper (ABIN518808)

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: "Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 973-85, (2013) (PubMed).

Details zu PFKFB3

Target: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Andere Bezeichnung: PFKFB3 (PFKFB3 Produkte)

Synonyme: IPFK2 antikoerper, PFK2 antikoerper, E330010H22Rik antikoerper, iPFK-2 antikoerper, uPFK-2 antikoerper, PFKFB3 antikoerper, zgc:73257 antikoerper, wu:fc31e01 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog antikoerper, PFKFB3 antikoerper, Pfkfb3 antikoerper, pfkfb3.S antikoerper, pfkfb3 antikoerper, PTRG_09894 antikoerper, Tsp_06710 antikoerper

Hintergrund: Full Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: IPFK2,PFK2

Gen-ID: 5209

NCBI Accession: NM_004566

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process