ETV6 Antikörper (N-Term)

Produktnummer ABIN504653

Produktdetails anti-ETV6 Antikörper

Target: ETV6 (Ets Variant 6 (ETV6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ETV6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WAENEFSLRP IDSNTFEMNG KALLLLTKED FRYRSPHSGD VLYELLQHIL

Kreuzreaktivität: Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ETV6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ETV6

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 452 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Andere Bezeichnung: ETV6 / TEL1 (ETV6 Produkte)

Synonyme: etv-6 antikoerper, tel antikoerper, tel/abl antikoerper, AW123102 antikoerper, AW557856 antikoerper, Tel antikoerper, TEL antikoerper, id:ibd2308 antikoerper, TEL/ABL antikoerper, cmlc2 antikoerper, mylc2a antikoerper, zgc:92755 antikoerper, ETS variant 6 antikoerper, ets variant 6 antikoerper, myosin, light chain 7, regulatory antikoerper, etv6 antikoerper, Etv6 antikoerper, ETV6 antikoerper, myl7 antikoerper

Hintergrund: ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. it contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TEL, TEL/ABL
Protein Interaction Partner: AP1M1, WDYHV1, UBC, SUMO1, NEDD8, ETV6, SUMO2, PIN1, HDAC6, SOX2, TRAF3, SOCS3, SOCS1, PDGFRB, ELAVL1, UBE2I, NCOR1, SIN3A, HDAC3, L3MBTL1, SMURF1, HDAC9, KAT5, FLI1, IRF8, SKP1, FBXL6, GAB2, GRB2, CRKL, ACTA1,
Protein Size: 452

Molekulargewicht: 53 kDa

Gen-ID: 2120

NCBI Accession: NM_001987, NP_001978

UniProt: P41212