RPS6KA2 Antikörper (Middle Region)

Produktnummer ABIN503865

Produktdetails anti-RPS6KA2 Antikörper

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSRQDVHLVK GAMAATYFAL NRTPQAPRLE PVLSSNLAQR RGMKRLTSTR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against RPS6KA2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 733 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPS6KA2

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Andere Bezeichnung: RPS6KA2 (RPS6KA2 Produkte)

Synonyme: HU-2 antikoerper, MAPKAPK1C antikoerper, RSK antikoerper, RSK3 antikoerper, S6K-alpha antikoerper, S6K-alpha2 antikoerper, p90-RSK3 antikoerper, pp90RSK3 antikoerper, 90kDa antikoerper, D17Wsu134e antikoerper, Rps6ka-rs1 antikoerper, Rsk3 antikoerper, p90rsk antikoerper, pp90rsk antikoerper, ribosomal protein S6 kinase A2 antikoerper, ribosomal protein S6 kinase, polypeptide 2 antikoerper, Rps6ka2 antikoerper, RPS6KA2 antikoerper

Hintergrund: RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3
Protein Interaction Partner: MAPK3, MAPK1, RPS6KA1, HSP90AA1, FLNC, CSNK2B, STXBP2, NQO2, UBC, RPS6KA2, JUN, FOS, SHANK1, BAD, MAGI1, L1CAM, MAP2K1, CREB1, CREBBP,
Protein Size: 733

Molekulargewicht: 81 kDa

Gen-ID: 6196

NCBI Accession: NM_021135, NP_066958

UniProt: Q15349

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades