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Carabin Antikörper (N-Term)

TBC1D10C Reaktivität: Human, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN503788
  • Target Alle Carabin (TBC1D10C) Antikörper anzeigen
    Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein
    Wirt
    • 9
    • 1
    Kaninchen
    Klonalität
    • 10
    Polyklonal
    Konjugat
    • 10
    Dieser Carabin Antikörper ist unkonjugiert
    Applikation
    • 10
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    MAQALGEDLV QPPELQDDSS SLGSDSELSG PGPYRQADRY GFIGGSSAEP
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rat: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TBC1D10C. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TBC1D10C
    Top Product
    Discover our top product TBC1D10C Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 446 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
    Andere Bezeichnung
    TBC1D10C (TBC1D10C Produkte)
    Synonyme
    CARABIN antikoerper, EPI64C antikoerper, 1810062O14Rik antikoerper, AI428527 antikoerper, RGD1311490 antikoerper, TBC1 domain family member 10C antikoerper, TBC1 domain family, member 10c antikoerper, TBC1 domain family, member 10C antikoerper, TBC1D10C antikoerper, Tbc1d10c antikoerper
    Hintergrund
    TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].
    Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN
    Protein Interaction Partner: NOTCH2NL, KRTAP13-1, KLHL12, KRTAP5-9, HOXA1, APP, PPP3R2,
    Protein Size: 446
    Molekulargewicht
    50 kDa
    Gen-ID
    374403
    NCBI Accession
    NM_198517, NP_940919
    UniProt
    Q8IV04
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