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Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) Antikörper

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Antigen
Synonyme GDAP1L1, MGC146673, dJ881L22.1, dJ995J12.1.1, Gdap1l
Epitop
N-Term
(3), (1), (1)
Reaktivität
Rind (Kuh), Hund, Human, Maus, Ratte (Rattus), Zebrafisch (Danio rerio)
(19), (7), (6)
Wirt
Kaninchen
(11), (8)
Klonalität
Polyklonal
Applikation
Western Blot (WB)
(17), (8), (6), (5), (3)
Pubmed 1 Publikation vorhanden
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Produkt-ID vom Hersteller Anmelden zum Anzeigen Neu
Menge 50 μg
Optionen
Lieferung nach Deutschland ( )
Verfügbarkeit Lieferung in 6 bis 8 Werktagen
Immunogen Synthetic peptide directed towards the N terminal of human GDAP1L1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977349.
Sequenz ERDVSLPQSE HKEPWFMRLN LGEEVPVIIH RDNIISDYDQ IIDYVERTFT
Homologie Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 70 %
Produktmerkmale This is a rabbit polyclonal antibody against GDAP1L1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung GDAP1L1 (GDAP1L1 Antibody Abstract)
Hintergrund The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. GDAP1L1 is similar in sequence to the human GDAP1 protein.The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein.
Molekulargewicht 42 kDa
Gen-ID 78997
NCBI Accession NP_076939, NM_024034
UniProt Q96MZ0
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 367 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 50 µL of distilled water.
Konzentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20 °C
Bilder des Herstellers
Western Blot (WB) image for anti-Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) Antikörper (ABIN503085) anti-Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) antibody
Allgemeine Veröffentlichungen Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Produktnummer ABIN503085
358,51 €
Zzgl. Versandkosten 20,00 € und MWSt

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