FXR2 Antikörper (Middle Region)

Produktnummer ABIN501987

Produktdetails anti-FXR2 Antikörper

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FXR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RGRRTGGPAY GPSSDVSTAS ETESEKREEP NRAGPGDRDP PTRGEESRRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FXR2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FXR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 673 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FXR2 Antikörper (ABIN501987)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu FXR2

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Andere Bezeichnung: FXR2 (FXR2 Produkte)

Synonyme: id:ibd5046 antikoerper, zgc:56215 antikoerper, zgc:77472 antikoerper, FMR1L2 antikoerper, FXR2P antikoerper, Fxr2h antikoerper, FMR1 autosomal homolog 2 antikoerper, fragile X mental retardation, autosomal homolog 2 antikoerper, FXR2 antikoerper, fxr2 antikoerper, Fxr2 antikoerper

Hintergrund: FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FMR1L2, FXR2P
Protein Interaction Partner: MORF4L1, FMR1, MRPL43, PRAM1, CEP44, HMBOX1, C1orf35, NIF3L1, TBC1D22B, CEP55, FAM90A1, PAF1, LASP1, POM121, FXR2, ZBTB22, AP1M1, SCEL, YES1, SRPK2, PIM1, PCBD1, MFAP1, LCP2, CDKL3, BAZ2B, CAMK2D, BYSL, C10orf62, MIA3, ZMAT2, SYT6, SYTL4, NDN, KIF1A, UBC,
Protein Size: 673

Molekulargewicht: 74 kDa

Gen-ID: 9513

NCBI Accession: NM_004860, NP_004851

UniProt: P51116