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TRIOBP Antikörper (Middle Region)

TRIOBP Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501329
  • Target Alle TRIOBP Antikörper anzeigen
    TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Schwein
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 8
    Dieser TRIOBP Antikörper ist unkonjugiert
    Applikation
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP
    Top Product
    Discover our top product TRIOBP Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 431 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
    Andere Bezeichnung
    TRIOBP (TRIOBP Produkte)
    Synonyme
    tara antikoerper, DFNB28 antikoerper, TARA antikoerper, dJ37E16.4 antikoerper, AI428493 antikoerper, EST478828 antikoerper, Tara antikoerper, mKIAA1662 antikoerper, TRIO and F-actin binding protein antikoerper, TRIO and F-actin-binding protein antikoerper, TRIO and F-actin binding protein L homeolog antikoerper, TRIO and F-actin binding protein-like antikoerper, TRIOBP antikoerper, LOC100354753 antikoerper, triobp.L antikoerper, TRIOBPL antikoerper, Triobp antikoerper
    Hintergrund
    TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
    Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
    Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
    Protein Size: 431
    Molekulargewicht
    47 kDa
    Gen-ID
    11078
    NCBI Accession
    NM_138632, NP_619538
    UniProt
    Q9H2D6
    Pathways
    Regulation of Actin Filament Polymerization
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