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UBE2N Antikörper (C-Term)

UBE2N Reaktivität: Human, Ratte, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501096
  • Target Alle UBE2N Antikörper anzeigen
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 37
    • 33
    • 31
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 47
    • 4
    • 1
    Kaninchen
    Klonalität
    • 39
    • 13
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2N Antikörper ist unkonjugiert
    Applikation
    • 19
    • 16
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects UBE2N / BLU.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    UBC13 antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human UBC13.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    Abstract
    UBE2N Produkte
    Synonyme
    UBC13 antikoerper, UbcH-ben antikoerper, UbcH13 antikoerper, 1500026J17Rik antikoerper, AL022654 antikoerper, BB101821 antikoerper, ube2n antikoerper, wu:fb11b03 antikoerper, wu:fc08b06 antikoerper, zgc:55726 antikoerper, ubc13 antikoerper, ubch-ben antikoerper, UBE2N antikoerper, ube2nl antikoerper, zgc:63901 antikoerper, ubiquitin conjugating enzyme E2 N antikoerper, ubiquitin-conjugating enzyme E2N antikoerper, ubiquitin conjugating enzyme E2 N S homeolog antikoerper, ubiquitin-conjugating enzyme E2Na antikoerper, ubiquitin-conjugating enzyme E2Nb antikoerper, UBE2N antikoerper, Ube2n antikoerper, ube2n.S antikoerper, ube2na antikoerper, LOC100533434 antikoerper, ube2n antikoerper, ube2nb antikoerper
    Hintergrund
    Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway (1). It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway (reviewed in 2). Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors (2,3). Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family (4-6). The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation (5).Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N
    Gen-ID
    7334
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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