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TRAF6 Antikörper (C-Term)

TRAF6 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501028
  • Target Alle TRAF6 Antikörper anzeigen
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 58
    • 31
    • 25
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 56
    • 5
    • 2
    Kaninchen
    Klonalität
    • 54
    • 9
    Polyklonal
    Konjugat
    • 40
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRAF6 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TRAF6 / RNF85 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Andere Bezeichnung
    TRAF6 / RNF85 (TRAF6 Produkte)
    Synonyme
    MGC:3310 antikoerper, RNF85 antikoerper, 2310003F17Rik antikoerper, AI851288 antikoerper, C630032O20Rik antikoerper, rnf85 antikoerper, traf6 antikoerper, xtraf6 antikoerper, CG10961 antikoerper, DTRAF2 antikoerper, Dmel\\CG10961 antikoerper, TRAF antikoerper, TRAF2 antikoerper, TRAF6 antikoerper, Traf2 antikoerper, dTRAF2 antikoerper, dTRAF6 antikoerper, dTraf2 antikoerper, dtraf2 antikoerper, GB10539 antikoerper, fi15f02 antikoerper, wu:fi15f02 antikoerper, zgc:63704 antikoerper, TNF receptor associated factor 6 antikoerper, TNF receptor-associated factor 6 antikoerper, TNF receptor associated factor 6 L homeolog antikoerper, TNF-receptor-associated factor 6 antikoerper, TNF receptor associated factor 6 S homeolog antikoerper, TRAF6 antikoerper, Traf6 antikoerper, traf6.L antikoerper, traf6 antikoerper, LOC551819 antikoerper, traf6.S antikoerper
    Hintergrund
    Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
    Gen-ID
    7189
    NCBI Accession
    NP_004611
    Pathways
    NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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