Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RIPK2 Antikörper (C-Term)

RIPK2 Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500601
  • Target Alle RIPK2 Antikörper anzeigen
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    Bindungsspezifität
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 508-522, C-Term
    Reaktivität
    • 69
    • 37
    • 20
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Human
    Wirt
    • 63
    • 7
    • 1
    Kaninchen
    Klonalität
    • 65
    • 6
    Polyklonal
    Konjugat
    • 41
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RIPK2 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 34
    • 25
    • 10
    • 10
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects RICK at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    RICK antibody was raised against a peptide corresponding to amino acids 508 to 522 of human origin.
    Isotyp
    IgG
    Top Product
    Discover our top product RIPK2 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 1: 500, an approximately 60 kDa band can be detected. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    Andere Bezeichnung
    RIPK2 (RIPK2 Produkte)
    Synonyme
    RIPK2 antikoerper, 2210420D18Rik antikoerper, CARD3 antikoerper, CARDIAK antikoerper, CCK antikoerper, D4Bwg0615e antikoerper, RICK antikoerper, RIP2 antikoerper, GIG30 antikoerper, receptor interacting serine/threonine kinase 2 antikoerper, receptor (TNFRSF)-interacting serine-threonine kinase 2 antikoerper, receptor-interacting serine-threonine kinase 2 antikoerper, RIPK2 antikoerper, Ripk2 antikoerper
    Hintergrund
    Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively, (1-3). RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1b. The messenger RNA of RICK is expressed in multiple human tissues (1).Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2
    Gen-ID
    8767
    UniProt
    O43353
    Pathways
    T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
Sie sind hier:
Kundenservice