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PERP Antikörper (C-Term)

PERP Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500475
  • Target Alle PERP Antikörper anzeigen
    PERP (TP53 Apoptosis Effector (PERP))
    Bindungsspezifität
    • 11
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 34
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 25
    • 9
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PERP Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 16
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects PERP.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    DEAE purified
    Immunogen
    PERP antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids (7-9).
    Isotyp
    IgG
    Top Product
    Discover our top product PERP Primärantikörper
  • Applikationshinweise
    ELISA. Western blot. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    PERP (TP53 Apoptosis Effector (PERP))
    Andere Bezeichnung
    PERP (PERP Produkte)
    Synonyme
    KCP1 antikoerper, KRTCAP1 antikoerper, PIGPC1 antikoerper, RP3-496H19.1 antikoerper, THW antikoerper, dJ496H19.1 antikoerper, 1110017A08Rik antikoerper, kcp1 antikoerper, krtcap1 antikoerper, pigpc1 antikoerper, thw antikoerper, fk24g11 antikoerper, wu:fk24g11 antikoerper, PERP antikoerper, PERP, TP53 apoptosis effector antikoerper, PERP, TP53 apoptosis effector S homeolog antikoerper, PERP antikoerper, Perp antikoerper, perp.S antikoerper, perp antikoerper
    Hintergrund
    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 , p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6), MTBP (7) and PERP (8), were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein (8-10). p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis (8). The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family (8).Synonyms: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22
    Gen-ID
    64058
    UniProt
    Q9JK95
    Pathways
    Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity
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