DHX58 Antikörper (C-Term)

Produktnummer ABIN500164

Produktdetails anti-DHX58 Antikörper

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects DHX58 at C-term.

Aufreinigung: Peptide affinity chromatography

Immunogen: LGP2 antibody was raised against a 12 amino acid peptide from near the carboxy terminus of human LGP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DHX58

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Andere Bezeichnung: DHX58 (DHX58 Produkte)

Synonyme: MGC82787 antikoerper, DHX58 antikoerper, lgp2 antikoerper, D11LGP2 antikoerper, D11lgp2e antikoerper, LGP2 antikoerper, RLR-3 antikoerper, B430001I08Rik antikoerper, D11Lgp2e antikoerper, LPG2 antikoerper, Lgp2 antikoerper, RGD1310093 antikoerper, DEXH-box helicase 58 L homeolog antikoerper, DExH-box helicase 58 antikoerper, probable ATP-dependent RNA helicase DHX58 antikoerper, DEXH (Asp-Glu-X-His) box polypeptide 58 antikoerper, DEXH-box helicase 58 antikoerper, dhx58.L antikoerper, DHX58 antikoerper, dhx58 antikoerper, LOC100566102 antikoerper, Dhx58 antikoerper

Hintergrund: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.Synonyms: ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, D11LGP2E, DHX58, LGP2, Protein D11Lgp2 homolog

Gen-ID: 79132

UniProt: Q96C10