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IRAK3 Antikörper

IRAK3 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500046
  • Target Alle IRAK3 Antikörper anzeigen
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Reaktivität
    • 58
    • 35
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 79
    • 7
    • 1
    Kaninchen
    Klonalität
    • 72
    • 15
    Polyklonal
    Konjugat
    • 39
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRAK3 Antikörper ist unkonjugiert
    Applikation
    • 72
    • 39
    • 13
    • 13
    • 10
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    IRAK-M antibody was raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M. IRAK-M antibody has no cross response to IRAK or IRAK2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human IRAK-M Peptide
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: 0.5 to 1 μg/mL. A 68 kDa major band can be detected. Immunohistochemistry: 2 μg/mL. .
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Andere Bezeichnung
    IRAK3 (IRAK3 Produkte)
    Synonyme
    IRAK3 antikoerper, si:dkey-150i15.2 antikoerper, ASRT5 antikoerper, IRAKM antikoerper, IrakM antikoerper, 4833428C18Rik antikoerper, AI563835 antikoerper, IRAK-M antikoerper, interleukin 1 receptor associated kinase 3 antikoerper, interleukin-1 receptor-associated kinase 3 antikoerper, IRAK3 antikoerper, irak3 antikoerper, Irak3 antikoerper
    Hintergrund
    Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors (1,2), which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M (3). IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.Synonyms: IL-1 receptor-associated kinase M, IRAK-3, IRAK-M, Interleukin-1 receptor-associated kinase 3
    Gen-ID
    11213
    UniProt
    Q9Y616
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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