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ITGA4 Antikörper (Center)

ITGA4 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500030
  • Target Alle ITGA4 Antikörper anzeigen
    ITGA4 (Integrin alpha 4 (ITGA4))
    Bindungsspezifität
    • 16
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 140
    • 104
    • 36
    • 19
    • 14
    • 10
    • 9
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 81
    • 56
    • 48
    Kaninchen
    Klonalität
    • 117
    • 70
    • 1
    Polyklonal
    Konjugat
    • 84
    • 18
    • 17
    • 14
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGA4 Antikörper ist unkonjugiert
    Applikation
    • 113
    • 62
    • 43
    • 40
    • 32
    • 25
    • 13
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to Integrin alpha 4.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Integrin alpha 4 antibody was raised against a 16 amino acid peptide from near the center of human Integrin alpha 4.
    Isotyp
    IgG
    Top Product
    Discover our top product ITGA4 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    ITGA4 (Integrin alpha 4 (ITGA4))
    Andere Bezeichnung
    CD49d / ITGA4 (ITGA4 Produkte)
    Synonyme
    CD49D antikoerper, IA4 antikoerper, LOC100219853 antikoerper, integrin subunit alpha 4 antikoerper, integrin alpha 4 antikoerper, integrin subunit alpha 4 S homeolog antikoerper, ITGA4 antikoerper, Itga4 antikoerper, itga4.S antikoerper
    Hintergrund
    The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha 4 chain associates with either beta 1 or beta 7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha 4 beta 1 and alpha 4 beta 7 is located on the alpha 4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha 4 beta 7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha 4 beta 1, the gut mucosal homing receptor for peripheral T cells. Despite its predicted molecular weight, Integrin alpha 4 will often run at higher molecular weight in SDS-PAGE. At least two isoforms are known to exist.Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4
    Gen-ID
    3676
    UniProt
    P13612
    Pathways
    Integrin Complex
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