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IL27 Antikörper (Center)

IL27 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500002
  • Target Alle IL27 Antikörper anzeigen
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 17
    • 14
    • 10
    Human, Maus
    Wirt
    • 16
    • 4
    Kaninchen
    Klonalität
    • 16
    • 4
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL27 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to IL-27.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    IL-27 antibody was raised against a 14 amino acid peptide from near the center of human IL-27.
    Isotyp
    IgG
    Top Product
    Discover our top product IL27 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Andere Bezeichnung
    Interleukin-27 / IL27A (IL27 Produkte)
    Synonyme
    IL-27 antikoerper, IL-27A antikoerper, IL27A antikoerper, IL27p28 antikoerper, IL30 antikoerper, p28 antikoerper, EUROIMAGE1875335 antikoerper, IL25 antikoerper, IL27 antikoerper, IL27w antikoerper, R33729_1 antikoerper, SF20 antikoerper, IL-27p28 antikoerper, Il30 antikoerper, interleukin 27 antikoerper, myeloid derived growth factor antikoerper, IL27 antikoerper, MYDGF antikoerper, Il27 antikoerper
    Hintergrund
    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
    Gen-ID
    246778
    NCBI Accession
    NP_663634
    UniProt
    Q8NEV9
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