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IL23A Antikörper (N-Term)

IL23A Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499998
  • Target Alle IL23A Antikörper anzeigen
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Bindungsspezifität
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 43
    • 18
    • 8
    • 1
    Human, Maus
    Wirt
    • 35
    • 8
    • 2
    • 1
    Kaninchen
    Klonalität
    • 38
    • 8
    Polyklonal
    Konjugat
    • 32
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL23A Antikörper ist unkonjugiert
    Applikation
    • 31
    • 20
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to Il-23.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.
    Isotyp
    IgG
    Top Product
    Discover our top product IL23A Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Andere Bezeichnung
    Interleukin-23 alpha / IL23A (IL23A Produkte)
    Synonyme
    IL-23 antikoerper, IL-23A antikoerper, IL23P19 antikoerper, P19 antikoerper, SGRF antikoerper, FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, p19 antikoerper, il23p19 antikoerper, IL23 antikoerper, interleukin 23 subunit alpha antikoerper, interleukin 37 antikoerper, interleukin 23, alpha subunit p19 antikoerper, IL23A antikoerper, IL37 antikoerper, Il23a antikoerper
    Hintergrund
    Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
    Gen-ID
    51561
    UniProt
    Q9NPF7
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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