Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GBL Antikörper

GBL Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499879
  • Target Alle GBL Antikörper anzeigen
    GBL (G protein beta subunit-like (GBL))
    Reaktivität
    • 51
    • 32
    • 29
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 62
    • 3
    • 2
    Kaninchen
    Klonalität
    • 66
    • 1
    Polyklonal
    Konjugat
    • 28
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GBL Antikörper ist unkonjugiert
    Applikation
    • 40
    • 26
    • 13
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    GbL antibody was raised against a 14 amino acid peptide from near the carboxy-terminus of human GbL.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human GbL / G beta protein subunit-like Peptide
    Isotyp
    IgG
    Top Product
    Discover our top product GBL Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    GBL (G protein beta subunit-like (GBL))
    Andere Bezeichnung
    LST8 / GBL (GBL Produkte)
    Synonyme
    gbl antikoerper, lts8 antikoerper, GBL antikoerper, GbetaL antikoerper, LST8 antikoerper, POP3 antikoerper, WAT1 antikoerper, 0610033N12Rik antikoerper, AA409454 antikoerper, AI505104 antikoerper, AI851821 antikoerper, Gbl antikoerper, fi37e04 antikoerper, wu:fi37e04 antikoerper, zgc:55455 antikoerper, zgc:85668 antikoerper, MTOR associated protein, LST8 homolog L homeolog antikoerper, MTOR associated protein, LST8 homolog antikoerper, MTOR associated protein, LST8 homolog (S. cerevisiae) antikoerper, mlst8.L antikoerper, MLST8 antikoerper, Mlst8 antikoerper, mlst8 antikoerper
    Hintergrund
    GbetaL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors (1). It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (reviewed in 2). Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation (reviewed in 3). TOR is normally associated with GβL and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis (3). The binding of GβL to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth (3).Synonyms: G protein beta subunit-like, Gable, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8
    Gen-ID
    64223
    UniProt
    Q9BVC4
    Pathways
    PI3K-Akt Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt
Sie sind hier:
Kundenservice