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TMC6 Antikörper (N-Term)

TMC6 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499806
  • Target Alle TMC6 Antikörper anzeigen
    TMC6 (Transmembrane Channel-Like 6 (TMC6))
    Bindungsspezifität
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TMC6 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to EVER1.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    EVER1 antibody was raised against a 14 amino acid peptide from near the amino terminus of human EVER1.
    Isotyp
    IgG
  • Applikationshinweise
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    TMC6 (Transmembrane Channel-Like 6 (TMC6))
    Andere Bezeichnung
    TMC6 / EVER1 (TMC6 Produkte)
    Synonyme
    EVER1 antikoerper, zgc:92610 antikoerper, MGC83549 antikoerper, ever1 antikoerper, EV1 antikoerper, EVIN1 antikoerper, LAK-4P antikoerper, D11Ertd204e antikoerper, transmembrane channel like 6 antikoerper, transmembrane channel-like 6b antikoerper, transmembrane channel like 6 L homeolog antikoerper, transmembrane channel-like gene family 6 antikoerper, TMC6 antikoerper, tmc6b antikoerper, tmc6.L antikoerper, tmc6 antikoerper, Tmc6 antikoerper
    Hintergrund
    Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance. At least four isoforms of EVER1 are known to exist. This EVER1 antibody does not cross-react with EVER2.Synonyms: EVIN1, Epidermodysplasia verruciformis protein 1, LAK-4, Transmembrane channel-like protein 6
    Gen-ID
    11322
    UniProt
    Q7Z403
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