DR3/LARD Antikörper (C-Term)

Produktnummer ABIN499756

Produktdetails anti-DR3/LARD Antikörper

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR3/LARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: DR3 antibody was raised against a peptide corresponding to amino acids 398 to 417 of human DR3.

Aufreinigung: DEAE

Immunogen: Human DR3 (C-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/500 to 1/1000. A 59 kDa band should be detected and has no crossreaction to other death receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: TNFRSF25 / DR3 / TRAMP (TNFRSF25 Produkte)

Synonyme: APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper

Hintergrund: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel cell death receptor has not yet been defined. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.Synonyms: AIR, APO3, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, Tumor necrosis factor receptor superfamily member 25, WSL, WSL1

Gen-ID: 8718

UniProt: Q93038

Pathways: Apoptose