Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Caspase 4 Antikörper (N-Term)

CASP4 Reaktivität: Human, Maus WB, IHC (p), IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499561
  • Target Alle Caspase 4 (CASP4) Antikörper anzeigen
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Bindungsspezifität
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 58
    • 33
    • 15
    • 14
    • 1
    Human, Maus
    Wirt
    • 77
    • 11
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 76
    • 15
    Polyklonal
    Konjugat
    • 54
    • 15
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Caspase 4 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 29
    • 27
    • 11
    • 9
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-4.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human Casp-4 / ICH-2 / ICE rel II / Mih1 (N-Terminus) Peptide
    Isotyp
    IgG
    Top Product
    Discover our top product CASP4 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: Casp-4 antibody can be used for the detection of Caspase-4 at 1 μg/mL. Depending on cell lines or tissues used, other cleavage products may be observed. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Andere Bezeichnung
    Caspase-4 (CASP4 Produkte)
    Synonyme
    ICE(rel)II antikoerper, ICEREL-II antikoerper, ICH-2 antikoerper, Mih1/TX antikoerper, TX antikoerper, Casp11 antikoerper, CASP13 antikoerper, CASP1 antikoerper, CASP4 antikoerper, Caspl antikoerper, ich-3 antikoerper, Casp4 antikoerper, caspase 4 antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, caspase-4 antikoerper, CASP4 antikoerper, Casp4 antikoerper, LOC100731032 antikoerper
    Hintergrund
    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1). Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18 (2,3). Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells (4). More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease (5).Synonyms: CASP4, ICE(rel)-II, ICH2, Protease ICH-2, Protease TX
    Gen-ID
    837
    UniProt
    P49662
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Sie sind hier:
Kundenservice