EIF5B Antikörper

Produktnummer ABIN498961

Produktdetails anti-EIF5B Antikörper

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of eIF5B protein. (region surrounding His1086)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EIF5B

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Andere Bezeichnung: EIF5B / IF2 (EIF5B Produkte)

Synonyme: CIF2 antikoerper, EIF5B antikoerper, MGC134193 antikoerper, im:6912504 antikoerper, si:ch211-254d18.3 antikoerper, AO090003000953 antikoerper, DDBDRAFT_0206214 antikoerper, DDBDRAFT_0234259 antikoerper, DDB_0206214 antikoerper, DDB_0234259 antikoerper, IF2 antikoerper, A030003E17Rik antikoerper, BC018347 antikoerper, eukaryotic translation initiation factor 5B antikoerper, translation initiation factor IF-2 antikoerper, EIF5B antikoerper, eif5b antikoerper, EDI_190850 antikoerper, AOR_1_1690154 antikoerper, CMU_007690 antikoerper, POSPLDRAFT_134975 antikoerper, POSPLDRAFT_134953 antikoerper, eIF5b antikoerper, MCYG_03474 antikoerper, PITG_20386 antikoerper, eif5B antikoerper, MGYG_03082 antikoerper, PGTG_13938 antikoerper, Eif5b antikoerper

Hintergrund: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.Synonyms: Eukaryotic translation initiation factor 5B, KIAA0741, Translation initiation factor IF-2, eIF-5B

Molekulargewicht: approx. 139 kDa

Gen-ID: 9669

NCBI Accession: NP_056988

UniProt: O60841