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VASP Antikörper (pSer238)

VASP Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498713
  • Target Alle VASP Antikörper anzeigen
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    Bindungsspezifität
    • 19
    • 17
    • 15
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer238
    Reaktivität
    • 138
    • 65
    • 58
    • 12
    • 11
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 116
    • 21
    • 2
    Kaninchen
    Klonalität
    • 111
    • 28
    Polyklonal
    Konjugat
    • 81
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VASP Antikörper ist unkonjugiert
    Applikation
    • 106
    • 51
    • 50
    • 28
    • 22
    • 18
    • 14
    • 14
    • 12
    • 11
    • 5
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of p-VASP protein, only when phosphorylated at Ser238.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Reinheit
    > 95 % by SDS-PAGE
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    Discover our top product VASP Primärantikörper
  • Applikationshinweise
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    Andere Bezeichnung
    VASP (VASP Produkte)
    Synonyme
    vasp antikoerper, MGC80889 antikoerper, wu:fb23b04 antikoerper, wu:fk84g05 antikoerper, zgc:110347 antikoerper, si:dkey-113g17.1 antikoerper, si:ch211-202c21.1 antikoerper, DDBDRAFT_0188463 antikoerper, DDBDRAFT_0229340 antikoerper, DDB_0188463 antikoerper, DDB_0229340 antikoerper, VASP antikoerper, vasodilator stimulated phosphoprotein S homeolog antikoerper, vasodilator stimulated phosphoprotein b antikoerper, protein enabled antikoerper, vasodilator-stimulated phosphoprotein antikoerper, vasodilator stimulated phosphoprotein a antikoerper, vasodilator stimulated phosphoprotein antikoerper, vasp.S antikoerper, vaspb antikoerper, LOC5573842 antikoerper, CpipJ_CPIJ004706 antikoerper, CpipJ_CPIJ004707 antikoerper, vasP antikoerper, vasp antikoerper, VASP antikoerper, vaspa antikoerper, Vasp antikoerper
    Hintergrund
    The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. A distantly related protein, VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with Actin-like filaments. VASP shares a limited degree of homology with the amino-terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is also phosphorylated on Serine 239 by cGMP-dependent protein kinase.Synonyms: Vasodilator-stimulated phosphoprotein
    Molekulargewicht
    approx. 48 kDa
    Gen-ID
    7408
    NCBI Accession
    NP_003361
    UniProt
    P50552
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation
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