NME1 Antikörper (Non-Metastatic Cells 1, Protein (NM23A) Expressed in)

Details for Product anti-NME1 Antibody No. ABIN498563, Anbieter: Anmelden zum Anzeigen
Antigen
  • AWD
  • GAAD
  • NB
  • NBS
  • NDKA
  • NDPK-A
  • NDPKA
  • NM23
  • NM23-H1
  • AL024257
  • NM23-M1
  • NM23A
  • NDPK-Z1
  • NM23-B
  • NM23-Z1
  • ndpkz1
  • nm23b
  • nme1
  • nme2
  • nme2b1
  • NME1
  • NME1-NME2
  • NM23-C1
  • ndpk-b
  • ndpkb
  • nm23-h2
  • nm23ndk
  • puf
  • NBR-A
  • NBR-B
  • NME1-1
  • nm23ndk-a
  • NDK I
  • NDPK I
  • T30A10.80
  • T30A10_80
  • NDP kinase I
  • NME/NM23 nucleoside diphosphate kinase 1
  • NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
  • non-metastatic cells 1, protein (NM23A) expressed in
  • NME/NM23 nucleoside diphosphate kinase 2 S homeolog
  • NME/NM23 nucleoside diphosphate kinase 2 L homeolog
  • nucleoside diphosphate kinase
  • nucleoside diphosphate kinase 1
  • NME1
  • Nme1
  • nme2b.1
  • nme2.S
  • nme2.L
  • LOC547870
  • NDPK1
  • LOC107790563
Reaktivität
Human, Maus, Ratte (Rattus)
292
53
50
14
9
8
6
4
4
3
3
2
2
1
1
Wirt
Kaninchen
145
142
6
2
2
Klonalität
Polyklonal
Konjugat
Dieser NME1 Antikörper ist unkonjugiert
12
12
8
7
6
6
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
250
125
88
63
40
14
13
12
10
7
6
2
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Spezifität This antibody detects endogenous levels of NM23-H1 protein. (region surrounding Tyr52)
Kreuzreaktivität (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Reinigung Affinity chromatography
Reinheit > 95 % by SDS-PAGE
Andere Bezeichnung NDP Kinase A (NME1 Antibody Abstract)
Hintergrund The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sublines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and -H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nucleasehypersensitive elements at positions 142 to 115 of the human c-Myc promotor.Synonyms: GAAD, Granzyme A-activated DNase, NDPKA, NM23, NME1, Nucleoside diphosphate kinase A, nm23-H1
Molekulargewicht approx. 20 kDa
Gen-ID 4830
NCBI Accession NP_000260
UniProt P15531
Forschungsgebiet Kinases/Phosphatases, Cancer, Transcription Factors
Pathways Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Applikationshinweise Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody (ABIN498563) Immunohistochemistry (IHC) analyzes of NM23-H1 antibody in paraffin-embedded h...
Western Blotting (WB) image for anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody (ABIN498563) Western blot (WB) analysis of NM23-H1 antibody in extracts from HeLa cells.
Haben Sie etwas anderes gesucht?