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TWEAK Antikörper

TNFSF12 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498411
  • Target Alle TWEAK (TNFSF12) Antikörper anzeigen
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Reaktivität
    • 63
    • 25
    • 15
    • 4
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 45
    • 11
    • 11
    • 2
    Kaninchen
    Klonalität
    • 56
    • 12
    • 1
    Polyklonal
    Konjugat
    • 40
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TWEAK Antikörper ist unkonjugiert
    Applikation
    • 40
    • 26
    • 17
    • 14
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of TWEAK protein. (region surrounding Pro73)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse.
    Aufreinigung
    Affinity chromatography
    Reinheit
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product TNFSF12 Primärantikörper
  • Applikationshinweise
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Andere Bezeichnung
    TWEAK / TNFSF12 (TNFSF12 Produkte)
    Synonyme
    APO3L antikoerper, DR3LG antikoerper, TWEAK antikoerper, Apo3l antikoerper, Dr3l antikoerper, Dr3lg antikoerper, Tweak antikoerper, TNF superfamily member 12 antikoerper, tumor necrosis factor (ligand) superfamily, member 12 antikoerper, TNFSF12 antikoerper, Tnfsf12 antikoerper
    Hintergrund
    TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placent,a lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.Synonyms: APO3 ligand, APO3L, DR3LG, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12
    Molekulargewicht
    approx. 27 kDa
    Gen-ID
    8742
    NCBI Accession
    NP_003800
    UniProt
    O43508
    Pathways
    Apoptose
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