MAPK15 Antikörper

Produktnummer ABIN498400

Produktdetails anti-MAPK15 Antikörper

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of ERK8 protein. (region surrounding Asp171)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS, pH 7.2, 0,05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MAPK15

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Andere Bezeichnung: MAPK15 (MAPK15 Produkte)

Synonyme: MGC138052 antikoerper, MGC99048 antikoerper, erk7 antikoerper, zgc:110345 antikoerper, ERK7 antikoerper, ERK8 antikoerper, BC048082 antikoerper, Erk7 antikoerper, ATMPK15 antikoerper, F25P22.9 antikoerper, F25P22_9 antikoerper, MAP kinase 15 antikoerper, mitogen-activated protein kinase 15 antikoerper, mitogen-activated protein kinase 15 L homeolog antikoerper, MAP kinase 15 antikoerper, MAPK15 antikoerper, mapk15.L antikoerper, mapk15 antikoerper, Tsp_00300 antikoerper, Mapk15 antikoerper, MPK15 antikoerper

Hintergrund: The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15

Molekulargewicht: approx. 60 kDa

Gen-ID: 225689

NCBI Accession: NP_620590

UniProt: Q8TD08