MKL1 Antikörper

Produktnummer ABIN498351

Produktdetails anti-MKL1 Antikörper

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MRTF-A protein. (region surrounding His11)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Abstract: MKL1 Produkte

Synonyme: MKL1 antikoerper, BSAC antikoerper, MAL antikoerper, MRTF-A antikoerper, Mrtf-a antikoerper, mrtf-a antikoerper, mrtfa antikoerper, AI852829 antikoerper, AMKL antikoerper, AW743281 antikoerper, AW821984 antikoerper, Bsac antikoerper, Mal antikoerper, Mrtf-A antikoerper, megakaryoblastic leukemia (translocation) 1 antikoerper, megakaryoblastic leukemia 1 protein antikoerper, megakaryoblastic leukemia (translocation) 1 S homeolog antikoerper, MKL (megakaryoblastic leukemia)/myocardin-like 1 antikoerper, MKL1 antikoerper, mkl1 antikoerper, Mkl1 antikoerper, mkl1.S antikoerper

Hintergrund: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A), also known as MKL1, interacts with SRF and stimulates its transcriptional activity.Synonyms: Basic SAP coiled-coil transcription activator, Bsac, MKL, Megakaryoblastic leukemia 1 protein homolog, Mkl1, Myocardin-related transcription factor A

Molekulargewicht: approx. 99 kDa

Gen-ID: 57591

NCBI Accession: NP_065882

UniProt: Q969V6