FOXE3 Antikörper

Produktnummer ABIN498337

Produktdetails anti-FOXE3 Antikörper

Target: FOXE3 (Forkhead Box E3 (FOXE3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of FOXE3 protein. (region surrounding Arg97)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % Sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FOXE3

Target: FOXE3 (Forkhead Box E3 (FOXE3))

Andere Bezeichnung: FOXE3 / FKHL12 (FOXE3 Produkte)

Synonyme: FOXE3 antikoerper, FKHL12 antikoerper, FREAC8 antikoerper, dyl antikoerper, rct antikoerper, FREAC-8 antikoerper, HFH7 antikoerper, HNF3 antikoerper, foxe4 antikoerper, lens1 antikoerper, lens1-A antikoerper, forkhead box E3 antikoerper, forkhead box E3 L homeolog antikoerper, foxe3 antikoerper, FOXE3 antikoerper, LOC100301611 antikoerper, Foxe3 antikoerper, foxe3.L antikoerper

Hintergrund: The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.Synonyms: FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8

Molekulargewicht: approx. 33 kDa

Gen-ID: 2301

NCBI Accession: NP_036318

UniProt: Q13461