PMP22 Antikörper

Produktnummer ABIN498164

Produktdetails anti-PMP22 Antikörper

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This detects endogenous levels of GAS3 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Andere Bezeichnung: PMP22 (PMP22 Produkte)

Synonyme: CMT1A antikoerper, CMT1E antikoerper, DSS antikoerper, GAS-3 antikoerper, HMSNIA antikoerper, HNPP antikoerper, Sp110 antikoerper, 22kDa antikoerper, Gas-3 antikoerper, Tr antikoerper, trembler antikoerper, pmp22 antikoerper, wu:fa04d03 antikoerper, wu:fa08d03 antikoerper, MGC80653 antikoerper, PMP22 antikoerper, MGC69407 antikoerper, id:ibd2630 antikoerper, wu:fb81f09 antikoerper, zgc:136919 antikoerper, peripheral myelin protein 22 antikoerper, peripheral myelin protein 22a antikoerper, peripheral myelin protein 22 S homeolog antikoerper, peripheral myelin protein 22b antikoerper, PMP22 antikoerper, Pmp22 antikoerper, pmp22a antikoerper, pmp22.S antikoerper, pmp22 antikoerper, pmp22b antikoerper

Hintergrund: PMP 22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.Synonyms: GAS-3, GAS3, Growth arrest-specific protein 3, PMP-22, Peripheral myelin protein 22

Molekulargewicht: approx. 22 kDa

Gen-ID: 5376

NCBI Accession: NP_000295

UniProt: Q01453