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MYB Antikörper (Internal Region)

MYB Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN498072
  • Target Alle MYB Antikörper anzeigen
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Bindungsspezifität
    • 15
    • 11
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 557-569, Internal Region
    Reaktivität
    • 117
    • 52
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Schwein
    Wirt
    • 97
    • 21
    • 3
    • 3
    Ziege
    Klonalität
    • 103
    • 21
    Polyklonal
    Konjugat
    • 80
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYB Antikörper ist unkonjugiert
    Applikation
    • 94
    • 58
    • 44
    • 24
    • 23
    • 13
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    C-HRDQTVKTQK ENT
    Spezifität
    This antibody is expected to recognize all reported isofoms (NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1, NP_001155132.1).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Pig.
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide corresponding to internal region of Human c-Myb Genename: MYB
    Top Product
    Discover our top product MYB Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 85 kDa in lysates of cell line Jurkat.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Andere Bezeichnung
    MYB (MYB Produkte)
    Synonyme
    Cmyb antikoerper, c-myb antikoerper, c-myb_CDS antikoerper, efg antikoerper, AI550390 antikoerper, M16449 antikoerper, cmyb antikoerper, xmyb antikoerper, MYB proto-oncogene, transcription factor antikoerper, myeloblastosis oncogene antikoerper, MYB proto-oncogene, transcription factor S homeolog antikoerper, v-myb avian myeloblastosis viral oncogene homolog antikoerper, MYB antikoerper, Myb antikoerper, myb.S antikoerper, myb antikoerper
    Hintergrund
    Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb
    Gen-ID
    4602
    NCBI Accession
    NP_005366
    UniProt
    P10242
    Pathways
    Chromatin Binding, Positive Regulation of Immune Effector Process
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