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GOPC Antikörper (C-Term)

GOPC Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN497983
  • Target Alle GOPC Antikörper anzeigen
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    Bindungsspezifität
    • 15
    • 10
    • 7
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 81
    • 32
    • 9
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 80
    • 1
    Kaninchen
    Klonalität
    • 72
    • 9
    Polyklonal
    Konjugat
    • 28
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GOPC Antikörper ist unkonjugiert
    Applikation
    • 43
    • 30
    • 30
    • 14
    • 14
    • 10
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes PIST (C-term).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse and Rat
    Aufreinigung
    Immunoaffinity Chromatography
    Immunogen
    PIST antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human PIST
    Isotyp
    IgG
    Top Product
    Discover our top product GOPC Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: PIST antibody can be used for the detection of PIST at 1-2 μg/mL. Positive Control: Rat Colon Cell Lysate. Immunohistochemistry on paraffin sections. Positive Control: Rat Colon Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    Andere Bezeichnung
    GOPC / PIST (GOPC Produkte)
    Synonyme
    DKFZp459H2130 antikoerper, 2210402P09Rik antikoerper, AI844555 antikoerper, CAL antikoerper, FIG antikoerper, GOPC1 antikoerper, PIST antikoerper, fe38f01 antikoerper, wu:fe38f01 antikoerper, zgc:56254 antikoerper, zgc:65853 antikoerper, dJ94G16.2 antikoerper, cal antikoerper, gopc1 antikoerper, pist antikoerper, golgi associated PDZ and coiled-coil motif containing antikoerper, golgi-associated PDZ and coiled-coil motif containing antikoerper, golgi-associated PDZ and coiled-coil motif containing S homeolog antikoerper, GOPC antikoerper, Gopc antikoerper, gopc antikoerper, gopc.S antikoerper
    Hintergrund
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6 (4-6). Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1 (6).Synonyms: CAL, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi-associated PDZ and coiled-coil motif-containing protein, PDZ protein interacting specifically with TC10
    Gen-ID
    57120
    NCBI Accession
    NP_001017408
    UniProt
    Q9HD26
    Pathways
    Maintenance of Protein Location, Asymmetric Protein Localization
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