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BRCA1 Antikörper (pSer988)

BRCA1 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN540547
  • Target Alle BRCA1 Antikörper anzeigen
    BRCA1 (Breast Cancer 1 (BRCA1))
    Bindungsspezifität
    • 22
    • 18
    • 15
    • 15
    • 14
    • 11
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer988
    Reaktivität
    • 192
    • 36
    • 25
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 161
    • 37
    • 2
    Kaninchen
    Klonalität
    • 165
    • 35
    Polyklonal
    Konjugat
    • 93
    • 18
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser BRCA1 Antikörper ist unkonjugiert
    Applikation
    • 126
    • 67
    • 42
    • 42
    • 41
    • 36
    • 29
    • 24
    • 22
    • 12
    • 12
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Verwendungszweck
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.
    Sequenz
    IKSpFV
    Spezifität
    BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Synthetic Peptide.
    Immunogen
    Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.
    Top Product
    Discover our top product BRCA1 Primärantikörper
  • Applikationshinweise
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Okada, Ouchi: "Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 2015-20, (2003) (PubMed).

    Tutt, Ashworth: "The relationship between the roles of BRCA genes in DNA repair and cancer predisposition." in: Trends in molecular medicine, Vol. 8, Issue 12, pp. 571-6, (2002) (PubMed).

    Scully, Livingston: "In search of the tumour-suppressor functions of BRCA1 and BRCA2." in: Nature, Vol. 408, Issue 6811, pp. 429-32, (2000) (PubMed).

  • Target
    BRCA1 (Breast Cancer 1 (BRCA1))
    Andere Bezeichnung
    BRCA1 / RNF53 (BRCA1 Produkte)
    Synonyme
    BRCAI antikoerper, BRCC1 antikoerper, BROVCA1 antikoerper, IRIS antikoerper, PNCA4 antikoerper, PPP1R53 antikoerper, PSCP antikoerper, RNF53 antikoerper, iris antikoerper, pscp antikoerper, brcai antikoerper, brcc1 antikoerper, rnf53 antikoerper, brca1 antikoerper, BRCA1 antikoerper, LOC100224649 antikoerper, BRCA1, DNA repair associated antikoerper, breast cancer 1 antikoerper, breast cancer 1, early onset antikoerper, breast cancer 1 L homeolog antikoerper, BRCA1 antikoerper, brca1 antikoerper, LOC755086 antikoerper, Brca1 antikoerper, brca1.L antikoerper
    Gen-ID
    672
    Pathways
    Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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