CDH10 Antikörper

Produktnummer ABIN4903221

Produktdetails anti-CDH10 Antikörper

Target: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDH10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CDH10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu CDH10

Target: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Andere Bezeichnung: CDH10 (CDH10 Produkte)

Synonyme: A830016G23Rik antikoerper, C030003B10Rik antikoerper, C030011H18Rik antikoerper, cadherin 10 antikoerper, Cdh10 antikoerper, CDH10 antikoerper

Gen-ID: 1008

UniProt: Q9Y6N8

Pathways: Cell-Cell Junction Organization