Interleukin 6 Antikörper (IL6) (AA 30-212)

Details for Product anti-IL6 Antibody No. ABIN4900155, Anbieter: Anmelden zum Anzeigen
Antigen
  • Il-6
  • ILg6
  • Ifnb2
  • BSF2
  • HGF
  • HSF
  • IFNB2
  • IL-6
  • CHIL-6
  • il6
  • interleukin 6
  • interleukin 6 (interferon, beta 2)
  • interleukin-6
  • Il6
  • IL6
  • il-6
Epitop
AA 30-212
66
49
27
20
15
15
15
14
13
10
10
10
9
8
7
7
6
6
5
3
3
3
2
1
1
1
1
1
1
Reaktivität
Human
577
240
113
37
29
26
21
10
7
7
7
6
4
3
3
2
1
Wirt
Maus
383
297
202
38
7
7
5
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Interleukin 6 Antikörper ist unkonjugiert
106
40
26
23
15
13
13
11
11
9
9
9
7
7
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
591
538
223
153
124
97
70
66
58
48
41
38
19
17
15
13
12
8
7
5
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen E. coli-derived recombinant human IL-6, Val30-Met212, Accession # P05231
Klon 1936
Isotyp IgG2b
Spezifität Detects human IL-6 in direct ELISAs. Does not cross-react with recombinant IL-6 from mouse, rat, or pig.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.20 EU per 1 μg of the antibody by the LAL method.
Andere Bezeichnung IL-6 (IL6 Antibody Abstract)
Hintergrund Alternative Names: B cell stimulatory factor-2, B-cell differentiation factor, BSF-2, BSF2CTL differentiation factor, CDF, HGFHSFIFNB2Hybridoma growth factor, IFN-beta-2, IL6, IL-6B-cell stimulatory factor 2, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
Gen-ID 3569
UniProt P05231
Forschungsgebiet Angiogenesis, Cytokines, Innate Immunity, Cancer
Pathways Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis
Applikationshinweise Neutralization 0.05-0.15 μg/mL
Intracellular Staining by Flow Cytometry 0.25 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Neutralization (Neut) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Cell Proliferation Induced by IL-6 and Neutralization by Human IL-6 Antibody. Recombi...
Flow Cytometry (FACS) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Detection of IL-6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclea...
Immunocytochemistry (ICC) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) IL-6 in Human PBMCs. IL-6 was detected in immersion fixed human peripheral blood mono...
Neutralization (Neut) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Cell Proliferation Induced by IL-6 and Neutralization by Human IL-6 Antibody. Recombi...
Flow Cytometry (FACS) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Detection of IL-6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclea...
Immunocytochemistry (ICC) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) IL-6 in Human PBMCs. IL-6 was detected in immersion fixed human peripheral blood mono...
Produkt verwendet in: Cheng, van Asten, Burns, Evans, Walter, Hashim, Hughes, Taams: "Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses." in: European journal of immunology, Vol. 46, Issue 9, pp. 2211-21, 2016 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Nakajima, Van Tin, Sato, Thach, Katano, Diep, Kumasaka, Thuy, Hasegawa, San, Kawachi, Liem, Suzuki, Sata: "Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 3, pp. 357-69, 2013 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Corvaisier, Delneste, Jeanvoine, Preisser, Blanchard, Garo, Hoppe, Barré, Audran, Bouvard, Saint-André, Jeannin: "IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation." in: PLoS biology, Vol. 10, Issue 9, pp. e1001395, 2012 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Steinbicker, Sachidanandan, Vonner, Yusuf, Deng, Lai, Rauwerdink, Winn, Saez, Cook, Szekely, Roy, Seehra, Cuny, Scadden, Peterson, Bloch, Yu: "Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation." in: Blood, Vol. 117, Issue 18, pp. 4915-23, 2011 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: "Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma." in: The Journal of allergy and clinical immunology, Vol. 123, Issue 1, pp. 239-48, 2009 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Rodier, Coppé, Patil, Hoeijmakers, Muñoz, Raza, Freund, Campeau, Davalos, Campisi: "Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion." in: Nature cell biology, Vol. 11, Issue 8, pp. 973-9, 2009 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC) (Probematerial (Species): Human).

Chong, Boehlke, Zheng, Zhang, Han, Zacks: "Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment." in: Investigative ophthalmology & visual science, Vol. 49, Issue 7, pp. 3193-200, 2008 (PubMed). Von den Autoren verwendete Methode: In vivo Studies (in vivo) (Probematerial (Species): Mouse (Murine)).

Ren, Lin, Li, Chen, Huang, Lui, Nicholls, Lan, Tam: "Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis." in: Histopathology, Vol. 46, Issue 6, pp. 659-67, 2005 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC) (Probematerial (Species): Human).

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