Interleukin 8 Antikörper (IL8) (AA 28-99)

Details for Product anti-IL8 Antibody No. ABIN4900105, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL8
  • K60
  • interleukin-8
  • il8
  • si:dkey-151b16.2
  • cxcli2
  • Il8
  • Scyb15
  • lungkine
  • weche
  • CXCL8
  • GCP-1
  • GCP1
  • LECT
  • LUCT
  • LYNAP
  • MDNCF
  • MONAP
  • NAF
  • NAP-1
  • NAP1
  • IL-8
  • AMCF-I
  • EMF-1
  • interleukin 8-like 1
  • interleukin 8
  • chemokine (C-X-C motif) ligand 1-like
  • chemokine (C-X-C motif) ligand 15
  • interleukin 8-like 2
  • interleukin-8-like
  • IL8L1
  • il8
  • IL8
  • LOC422654
  • Cxcl15
  • Il8
  • IL8L2
  • IL*08-02
Epitop
AA 28-99
52
31
23
14
13
11
8
7
6
5
4
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
420
31
24
19
18
15
14
9
8
7
6
5
4
4
4
1
1
1
1
1
Wirt
Maus
309
221
9
6
6
5
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Interleukin 8 Antikörper ist unkonjugiert
60
47
16
10
6
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut), Western Blotting (WB)
373
355
127
96
37
35
35
32
26
23
23
15
13
12
10
5
4
3
2
2
2
2
2
2
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen E. coli-derived recombinant human IL-8/CXCL8, Ser28-Ser99, Accession # P10145
Klon 6217
Isotyp IgG1
Spezifität Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100 % cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Andere Bezeichnung CXCL8/IL-8 (IL8 Antibody Abstract)
Hintergrund Alternative Names: 3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, MDNCF, MDNCFb-ENAP, member 8, MONAPGCP1, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
Gen-ID 3576
UniProt P10145
Forschungsgebiet Angiogenesis, Cytokines, Innate Immunity, Cancer
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
Applikationshinweise Western Blot 1 μg/mL
Neutralization 0.08-0.4 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 2-8 μg/mL
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Neutralization (Neut) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900105) Chemotaxis Induced by CXCL8/IL-8 and Neutralization by Human CXCL8/IL-8 Antibody. Rec...
Immunocytochemistry (ICC) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900105) CXCL8/IL-8 in Human PBMCs. CXCL8/IL-8 was detected in immersion fixed human periphera...
Neutralization (Neut) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900105) Chemotaxis Induced by IL-8/CXCL8 and Neutralization by Human IL-8/CXCL8 Antibody. Rec...
Immunocytochemistry (ICC) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900105) IL-8/CXCL8 in Human PBMCs. IL-8/CXCL8 was detected in immersion fixed human periphera...
Produkt verwendet in: Delitto, Delitto, DiVita, Pham, Han, Hartlage, Newby, Gerber, Behrns, Moldawer, Thomas, George, Brusko, Mathews, Liu, Trevino, Hughes, Wallet: "Human Pancreatic Cancer Cells Induce a MyD88-Dependent Stromal Response to Promote a Tumor-Tolerant Immune Microenvironment." in: Cancer research, Vol. 77, Issue 3, pp. 672-683, 2016 (PubMed). Von den Autoren verwendete Methode: Biochemical Assay (BCA) (Probematerial (Species): Human).

Han, Li, Xu, Islam, Khang, Del Sorbo, Lee, Szaszi, Zhong, Slutsky, Li, Zhang: "Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells." in: Scientific reports, Vol. 6, pp. 31087, 2016 (PubMed). Von den Autoren verwendete Methode: Immunoprecipitation (IP) (Probematerial (Species): Escherichia coli (E. coli)).

Jing, Xu, Chen, Zhong, Huang, Zhang, Guo, Yang, Ding, Chen, Huang: "The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer." in: PLoS ONE, Vol. 11, Issue 4, pp. e0152789, 2016 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Chao, Sun, Peng, Wu: "Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells." in: International journal of molecular sciences, Vol. 17, Issue 8, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Voltolini, Battersby, Novembri, Torricelli, Severi, Petraglia, Norman: "Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition." in: Endocrinology, Vol. 156, Issue 2, pp. 670-9, 2015 (PubMed). Von den Autoren verwendete Methode: ELISA (Capture) (ELISA (Capture)) (Probematerial (Species): Human).

Takeuchi, Baghdadi, Tsuchikawa, Wada, Nakamura, Abe, Nakanishi, Usui, Higuchi, Takahashi, Inoko, Sato, Takano, Shichinohe, Seino, Hirano: "Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer." in: Cancer research, Vol. 75, Issue 13, pp. 2629-40, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Gouwy, De Buck, Pörtner, Opdenakker, Proost, Struyf, Van Damme: "Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines." in: European journal of immunology, Vol. 45, Issue 1, pp. 101-12, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Chen, Min, Wang, Zhao, Chen, Qin, Chen, Shen, Tang, Gan, Ruan, Sun, Qin, Gu: "Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop." in: Cancer research, Vol. 75, Issue 18, pp. 3832-41, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

McElvaney, OReilly, White, Lacey, Pohl, Gerlza, Bergin, Kerr, McCarthy, OBrien, Adage, Kungl, Reeves, McElvaney: "The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis." in: Molecular immunology, Vol. 63, Issue 2, pp. 550-8, 2014 (PubMed). Von den Autoren verwendete Methode: Biochemical Assay (BCA) (Probematerial (Species): Human).

Khanna, Chung, Neves, Robertson, Dong: "CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas." in: Oncogene, Vol. 33, Issue 22, pp. 2898-908, 2014 (PubMed). Von den Autoren verwendete Methode: ELISA (Capture) (ELISA (Capture)) (Probematerial (Species): Human).

Kuravi, McGettrick, Satchell, Saleem, Harper, Williams, Rainger, Savage: "Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 1, pp. 234-43, 2014 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Nakajima, Van Tin, Sato, Thach, Katano, Diep, Kumasaka, Thuy, Hasegawa, San, Kawachi, Liem, Suzuki, Sata: "Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 3, pp. 357-69, 2013 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Sahlander, Larsson, Palmberg: "Daily exposure to dust alters innate immunity." in: PLoS ONE, Vol. 7, Issue 2, pp. e31646, 2012 (PubMed). Von den Autoren verwendete Methode: ELISA (ELISA) (Probematerial (Species): Human).

Gelderblom, Weymar, Bernreuther, Velden, Arunachalam, Steinbach, Orthey, Arumugam, Leypoldt, Simova, Thom, Friese, Prinz, Hölscher, Glatzel, Korn, Gerloff, Tolosa, Magnus: "Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke." in: Blood, Vol. 120, Issue 18, pp. 3793-802, 2012 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Meda, Molla, De Pizzol, Regano, Maione, Capano, Locati, Mantovani, Latini, Bussolino, Giraudo: "Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 4081-92, 2012 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Bellini, Marini, Bianchetti, Barczyk, Schmidt, Mattoli: "Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients." in: Mucosal immunology, Vol. 5, Issue 2, pp. 140-9, 2012 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Nicolaidou, Wong, Redpath, Ersek, Baban, Williams, Cope, Horwood: "Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation." in: PLoS ONE, Vol. 7, Issue 7, pp. e39871, 2012 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Xu, Joo, Clayton, Dullaers, Herve, Blankenship, De La Morena, Balderas, Picard, Casanova, Pascual, Oh, Banchereau: "Macrophages induce differentiation of plasma cells through CXCL10/IP-10." in: The Journal of experimental medicine, Vol. 209, Issue 10, pp. 1813-23, S1-2, 2012 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Zepp, Nold-Petry, Dinarello, Nold: "Protection from RNA and DNA viruses by IL-32." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 4110-8, 2011 (PubMed). (Probematerial (Species): Human).

Chang, Al-Alwan, Risse, Roussel, Rousseau, Halayko, Martin, Hamid, Eidelman: "TH17 cytokines induce human airway smooth muscle cell migration." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 4, pp. 1046-53.e1-2, 2011 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

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